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Should we evaluate intestinal microbiota of pediatric patients undergoing hematopoietic stem cell transplantation?

Bone Marrow Transplantation volume 55, pages 1506–1508 (2020)Cite this article

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The interaction of gut microbiota and hematopoietic stem cell transplantation (HSCT) has been studied in several aspects, as composition, diversity, and metabolics products of microbiota. The present work aimed to characterize the gut microbiota of pediatric patients prior to HSCT in a university hospital in South of Brazil. Until now, it is the first study in Brazil about the topic.

Sampling was performed for convenience. Patients between 4- and 17-years-old undergoing HSCT in the given period were invited to participate. We collected the sample once the patient was admitted. Patients without adequate fecal sample were excluded from the study. Clinical information was obtained from the medical records, within 90 days after transplantation.

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Acknowledgements

We would like to thank the Fundo de Investimento a Pesquisa (FIPE / HCPA) for funding this study.

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Authors and Affiliations

  1. Programa de Pós Graduação em Saúde da Criança e do Adolescente, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil

    Iuri Vicente Camargo Morkis & Liane Esteves Daudt

  2. Hospital de Clínicas de Porto Alegre, Porto Alegre, Brazil

    Bruna de Mello Vicente, Muriel Habigzang, Priscila de Oliveira da Silva, Fernanda Scherer, Alessandra Paz, Mariana Bohns Michalowski & Liane Esteves Daudt

  3. Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil

    Bruna de Mello Vicente, Muriel Habigzang, Mariana Bohns Michalowski & Liane Esteves Daudt

Authors
  1. Iuri Vicente Camargo Morkis
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  2. Bruna de Mello Vicente
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  3. Muriel Habigzang
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  4. Priscila de Oliveira da Silva
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  5. Fernanda Scherer
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  6. Alessandra Paz
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  7. Mariana Bohns Michalowski
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  8. Liane Esteves Daudt
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Correspondence to Iuri Vicente Camargo Morkis.

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The authors declare that they have no conflict of interest.

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Study conducted at Unidade de Ambiente Protegido, at Hospital de Clínicas de Porto Alegre

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Morkis, I.V.C., Vicente, B.d.M., Habigzang, M. et al. Should we evaluate intestinal microbiota of pediatric patients undergoing hematopoietic stem cell transplantation?. Bone Marrow Transplant 55, 1506–1508 (2020). https://doi.org/10.1038/s41409-019-0727-6

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  • DOI: https://doi.org/10.1038/s41409-019-0727-6

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