This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 12 print issues and online access
$259.00 per year
only $21.58 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
References
Product Information. ALKERAN® ApoPharm USA Inc, 2011.
High Dose Melphalan Guideline. South West Clinical Network NHS, 2017. http://www.swscn.org.uk/wp/wp-content/uploads/2014/12/High-dose-melphlan.pdf. Accessed March 2019.
Castagna L, Crocchiolo R, Giordano L, Bramanti S, Carlo-Stella C, Sarina B, et al. High-dose melphalan with autologous stem cell support in refractory Hodgkin lymphoma patients as a bridge to second transplant. Bone Marrow Transplant. 2015;50:499–504.
McElwain TJ, Hedley DW, Burton G, Clink HM, Gordon MY, Jarman M, et al. Marrow autotransplantation accelerates haematological recovery in patients with malignant melanoma treated with high dose melphalan. Br J Cancer. 1979;40:72–80.
McElwain TJ, Powles RL. High-dose intravenous melphalan for plasma-cell leukaemia and myeloma. Lancet. 1983;322:822–4.
Ardiet C, Tranchand B, Biron P, Rebattu P, Philip T. Pharmacokinetics of high-dose intravenous melphalan in children and adults with forced diuresis. Cancer Chemother Pharm. 1986;16:300–5.
Segeren CM, Sonneveld P, van der Holt B, Vellenga E, Croockewit AJ, Verhoef GEG, et al. Overall and event-free survival are not improved by the use of myeloablative therapy following intensified chemotherapy in previously untreated patients with multiple myeloma: a prospective randomized phase 3 study. Blood. 2003;101:2144–51.
eviQ. Guidelines. www.eviq.org.au
Kidney Disease: Improving Global Outcomes (KDIGO) Acute Kidney Injury Work Group. KDIGO Clinical Practice Guideline for Acute Kidney Injury. Kidney International Supplements. 2012;2:1.
Acknowledgements
We wish to acknowledge ESA International and the Leukaemia Foundation for their financial support for the presentation of this study at the European Society for Blood and Marrow Transplantation Meeting 2018.
Author information
Authors and Affiliations
Corresponding author
Ethics declarations
Conflict of interest
The authors declare that they have no conflict of interest.
Additional information
Publisher’s note: Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.
Rights and permissions
About this article
Cite this article
Nakagaki, M., Button, E., Keating, A. et al. Hyperhydration is not necessary for high-dose melphalan in stem cell transplantation. Bone Marrow Transplant 55, 827–829 (2020). https://doi.org/10.1038/s41409-019-0586-1
Revised:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1038/s41409-019-0586-1