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Maternal obesity and cesarean section delivery: additional risk factors for neonatal hypoglycemia?

Journal of Perinatology volume 39, pages 1057–1064 (2019)Cite this article

Subjects

Abstract

Objectives

To determine (1) whether higher maternal body mass index (BMI) and Cesarean (C) Section mode of delivery are associated with neonatal hypoglycemia (NH) and (2) whether timing of NH onset differs by risk factors.

Study Design

Retrospective cohort study (n = 4602) to determine the odds of NH, NH requiring IV dextrose and timing of NH onset among infants with established and plausible (BMI and C-section) risk factors.

Result

Infants born to class III obese mothers had higher odds of NH (OR 1.3, 95% CI 1.0–1.8) and of requiring IV dextrose (OR 2.2, 95% CI 1.2–3.9). Infants born via C-section had higher odds of requiring IV dextrose (OR 1.4, 95% CI 1.1–1.9). Infants who were delivered to high BMI mothers and by C-section developed NH earlier than the reference group.

Conclusion

Determining the predictors and timing of NH onset may help develop tailored evaluation and management strategies for at-risk neonates.

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Funding

Dr. Sen is supported by K23 HD 074648.

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Authors and Affiliations

  1. Department of Pediatric Newborn Medicine, Brigham and Women’s Hospital, Brigham and Women’s Hospital, Boston, MA, USA

    Daria Turner, Carmen Monthé-Drèze, Sara Cherkerzian, Katherine Gregory & Sarbattama Sen

  2. Harvard Medical School, Brigham and Women’s Hospital, Boston, MA, USA

    Carmen Monthé-Drèze, Katherine Gregory & Sarbattama Sen

  3. Department of Nursing, Brigham and Women’s Hospital, Boston, MA, USA

    Katherine Gregory

Authors
  1. Daria Turner
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  2. Carmen Monthé-Drèze
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  5. Sarbattama Sen
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Correspondence to Sarbattama Sen.

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Turner, D., Monthé-Drèze, C., Cherkerzian, S. et al. Maternal obesity and cesarean section delivery: additional risk factors for neonatal hypoglycemia?. J Perinatol 39, 1057–1064 (2019). https://doi.org/10.1038/s41372-019-0404-z

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