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The death knell of inhaled nitric oxide to prevent bronchopulmonary dysplasia?

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References

  1. Cole FS, Alleyne C, Barks JDE, Boyle RJ, Carroll JL, Dokken D, et al. NIH Consensus Development conference statement: inhaled nitric-oxide therapy for premature infants. Pediatrics. 2011;127:363–9.

    Article  PubMed  Google Scholar 

  2. Askie LM, Ballard RA, Cutter GR, Dani C, Elbourne D, Field D, et al. Inhaled nitric oxide in preterm infants: an individual-patient data meta-analysis of randomized trials. Pediatrics. 2011;128:729–39.

    Article  PubMed  PubMed Central  Google Scholar 

  3. Ballard RA, Keller RL, Black DM, Ballard PL, Merrill JD, Eichenwald EC, et al. Randomized trial of late surfactant treatment in ventilated preterm infants receiving inhaled nitric oxide. J Pediatr. 2016;168:23–9.

    Article  PubMed  CAS  Google Scholar 

  4. Hasan SU, Potenziano J, Konduri GG, Perez JA, Van Meurs KP, Walker MW, et al. Effect of inhaled nitric oxide on survival without bronchopulmonary dysplasia in preterm infants: a randomized clinical trial. JAMA Pediatr. 2017;171:1081–9.

    Article  PubMed  Google Scholar 

  5. Ballard RA, Truog WE, Cnaan A, Martin RJ, Ballard PL, Merrill JD, et al. Inhaled nitric oxide in preterm infants undergoing mechanical ventilation. N Engl J Med. 2006;355:343–53.

    Article  PubMed  CAS  Google Scholar 

  6. Schreiber MD, Gin-Mestan K, Marks JD, Huo D, Lee G, Srisuparp P. Inhaled nitric oxide in premature infants with the respiratory distress syndrome. N Engl J Med. 2003;349:2099–107.

    Article  PubMed  CAS  Google Scholar 

  7. Askie LM, Davies LC, Schreiber MD, Hibbs AM, Ballard PL, Ballard RA. Race effects of inhaled nitric oxide in preterm infants: an individual participant data meta-analysis. J Pediatr. https://doi.org/10.1016/j.jpeds.2017.10.004. 2017.

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Correspondence to Kent Willis.

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Willis, K., Peravali, S. & Weems, M. The death knell of inhaled nitric oxide to prevent bronchopulmonary dysplasia?. J Perinatol 38, 633–635 (2018). https://doi.org/10.1038/s41372-018-0071-5

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