The Journal of Human Genetics published 167 papers in 2018. We prepared a special issue describing “Advances in inborn errors of metabolism” in 2018, which was published in February 2019. I would like to express my sincere appreciation to guest editors, Drs. Toshiyuki Fukao and Kimitoshi Nakamura, and all the contributors for their great work. I hope the special issue will attract attention to a broad readership.

In 2018, we celebrated Professor Tasuku Honjo receiving 2018’s Nobel Laureate in Physiology or Medicine. His outstanding achievements in discovery of cancer therapy by inhibition of negative immune regulation will open up a new strategy of cancer therapy.

In 2019, we are planning a special issue dealing with a new technology in human genetics researches. I look forward to it and also to receiving more exciting manuscripts for the Journal of Human Genetics from all over the world.