Insulin resistance and the concomitat hyperinsulinemia have been implicated in the pathogenesis of hypertension, both being components of metabolic syndromes associated to obesity. The aim of this study was to evaluate the insulin levels response to oral glucose tolerance test (OGTT) in a population of children and adolescents with hypertension. Patients with hypertension (systolic or diastolic higher than 95th Plo, Task Force patterns) characterized as essential were included. According to BMI they were classified into a) hypertense with normal BMI (NH) y b) hypertense with BMI >85 Plo (Ob H). Two control groups matched by age and BMI were included: C) control group with normal BMI (NC) and d) control group with BMI>85Plo (ObC). The insulin response during OGTT was evaluate by calculating the area under the curve and the insulinogenic index (insulin area/glucose area). Results: Table

Table 1 No caption available.
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Conclusions: There was a significant difference in the insulin area with the non-obese group between the hypertense and the control group that is not evident in the obese group. However according to the multiple regression analysys the insulin area correlated significantly with hyperhension, in spite of the IMC.