Abstract
The effects of hypoxemia (HO, 8% O2) followed by resuscitation with 21% or 100% O2 on retinal (RBF) and choroidal blood flow (ChBF) were studied in 19 newborn piglets with the microsphere method. When base excess reached - 20 mmol/L or systolic blood pressure fell below 30 mmHg, the piglets were randomly resuscitated with either 21% O2 (n=10) or 100% O2, (n=9) for 25 min followed by 21% O2, in both groups. RBF and ChBF were measured at baseline (Bl), at the end of HO, and 5 min, 20 min and 60 min of reoxygenation. Flow values were (ml/min/100g, mea±SD) :
HO significantly decreased ChBF, but not RBF. RBF significantly increased during 5 and 20 min of reoxygenation, while in ChBF this increase was only seen at 5 min of reoxgenation.
Conclusion: We could not demonstrate any significant differences in RBF or ChBF between two groups of hypoxemic newborn piglets reoxygenated with 21% or 100% O2.
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Odden, JP., Rootwelt, T., Hall, C. et al. RETINAL AND CHOROIDAL BLOOD FLOW DURING HYPOXEMIA AND REOXYGENATION WITH 21% AND 100% O2 IN THE NEWBORN PIGLET. Pediatr Res 35, 276 (1994). https://doi.org/10.1203/00006450-199402000-00130
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DOI: https://doi.org/10.1203/00006450-199402000-00130