Abstract
Head trauma can damage the hypothalamus as well as pituitary gland, which can in effect lead to disorders in secretion of tropic hormones or to disfunction of the pituitary itself. The aim of the study was evaluate the frequency and types of hormonal disorders after head injury in children. The study was conducted on 77 patients 10.8-8 yr.) with collection of auxological data and hormonal stimulation tests the insulin-hypoglicemia, the GRF 1-29, the TRH and GnRH test and serum and urine osmolality) which were carried out from 1 month to 7 yr. after the injury was sustained. Results are presented on tables.
Only 8/49 patients with hormonal disturbances had clinical symptoms - 3 showed height deficiency, I precocious puberty and 2 - symptoms of diabetes insipidus. Fourty one patients showed biochemical evidences of hormonal disfunction only. Our data confirmed that the regulation of GH secretion is the most sensitive to injury - mainly on the hypothalamic level, and indicates that routine hormonal diagnostic tests are justified, especially in children who have suffered serious head trauma with prolonged loss of consciousness.
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Ruszcynska-Wolska, A., Romer, T., Ginalska-Halinowska, H. et al. DISORDERS OF HYPOTHALAHO-PITUITARY FUNCTION AFTER HEAD INJURY IN CHILDREN. Pediatr Res 33 (Suppl 5), S28 (1993). https://doi.org/10.1203/00006450-199305001-00147
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DOI: https://doi.org/10.1203/00006450-199305001-00147