Abstract
To determine the effects of definitive operation for Ebstein's anomaly upon rest and exercise cardiorespiratory function, we performed cycle exercise studies on 38 patients with Ebstein's anomaly prior to operation and 10 patients after operation. All but 2 of the postop studies represented a maximal cardiorespiratory effort. Mean age of the preop group was 15.5 years and the postop group 13.6 years. Atrial septal defects were present in 31 of 38 preop and 0 of 10 postop patients. Seven of 10 postop patients had tricuspid valvuloplasty and 3 had valve replacement. All existing atrial septal defects were closed. Comparing pre to postop studies exercise duration increased* from 49.5 ± 21 to 77.9 ± 15% of predicted and maximum oxygen consumption increased* from 20.9 ± 7 to 27.2 ± 7 cc/kg/min. Rest systemic arterial oxygen saturation increased* from 87 ± 9 to 95 ± 3% and exercise saturation increased* from 77 ± 15 to 94 ± 3%. Maximum exercise heart rate was 80 ± 11 preop and 84 ± 13% of predicted postop. Rest ventilatory equivalent for oxygen (VE/VO2) decreased* from 48 ± 13 preop to 38 ± 6 postop and exercise VE/VO2 decreased* from 53 ± 23 preop to 38 ± 6 postop. Definitive operation (tricuspid valvuloplasty or replacement and ASD closure) results in significant improvement of exercise tolerance and normalization of systemic arterial oxygen saturation, and reduction of excess ventilation at rest and during exercise.
* = P<0.05 ± = standard deviation
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Driscoll, D., Mottram, C. & Danielson, G. EBSTEIN'S ANOMALY: PRE AND POSTOPERATIVE EXERCISE CARDIORESPIRATORY FUNCTION. Pediatr Res 21 (Suppl 4), 189 (1987). https://doi.org/10.1203/00006450-198704010-00139
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DOI: https://doi.org/10.1203/00006450-198704010-00139