Abstract
Superior mesenteric (Mes), femoral (Fem) and renal (Ren) arterial blood flow (F) responses to feeding following H (15% blood volume) were studied in piglets, 1, ≤2 days (n=7) and 11, 2-4 wks old (n=9) using electromagnetic probes. Heart rate (HR), ECG, aortic pressure (AoP), temperature and blood gases were simultaneously monitored. Following H, AoP and F decreased while HR increased. 30 min following H, milk formula was gavage fed (26 ml/kg) and F(ml/min) increases from control were: (Mean ± S.E.)
+p<.05 value vs control, *p<.05 Group I. vs II
Postprandially, Mes vascular resistance (R) decreased in older animals. RenF, AoP and other R di.d not change significantly while HR tended to increase in both ages. Pulse pressure increased in older pigs. The results suggest age-related difference in the postprandial Mes and possibly Fem vascular responses of piglets following H. Thus, H may adversely affect Mes vascular response of heonates to feeding during first days of life.
Supported by NIH Grant HL-20864.
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Yao, A., Gootman, P., Pierce, P. et al. 754 EFFECTS OF HEMORRHAGE (H) ON THE POSTPRANDIAL REGIONAL VASCULAR RESPONSES OF DEVELOPING PIGLETS. Pediatr Res 19, 236 (1985). https://doi.org/10.1203/00006450-198504000-00784
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DOI: https://doi.org/10.1203/00006450-198504000-00784