Abstract
ABSTRACT: Increasing reliance is being placed on the use of quantitative epidemiological methods in the conduct and evaluation of pediatric research. The basic design features of two common types of observational studies, the case-control study and the cohort study, are reviewed. Advantages and disadvantages of these two study designs are discussed with emphasis on aspects such as the selection of comparison groups, avoiding selection and recall bias, gathering exposure information, controlling for potentially confounding factors, and methods of analysis. Appreciation of the salient features of these study design approaches should aid the clinician/researcher in the conduct of research endeavors as well as in critically reviewing the medical literature.
Similar content being viewed by others
Article PDF
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Goldberg, R., Pastides, H., Curtis Ellison, R. et al. Uses of the Case-Control and Cohort Epidemiological Approaches in Pediatric Practice and Research. Pediatr Res 19, 787–790 (1985). https://doi.org/10.1203/00006450-198508000-00001
Received:
Accepted:
Issue Date:
DOI: https://doi.org/10.1203/00006450-198508000-00001
This article is cited by
-
Case-control studies in pediatric epidemiology: Parent surrogates and potential pitfalls of inaccurate and selective recall
Sozial- und Pr�ventivmedizin SPM (1992)