Abstract
We have examined the course of systemic BP over the first 48 hrs of life for LBW infants (≤1500gms) in relation to IVH. Thirty-four patients suffering a severe hemorrhage (grades 3 or 4) were matched for the severity of respiratory illness with an equal number of patients who developed a minor hemorrhage (grades 1 or 2) and an equal number who had no hemorrhage. All patients required mechanical ventilation for at least 24 hrs and the degree of respiratory illness was comparable in all three groups. Blood pressure was recorded hourly from indwelling arterial lines in the majority of patients (95%) and measured intermittently by oscillometry (Narco) in the remainder. There were no differences in the average systolic (S), diastolic (D) or mean (M) BP between the 3 groups on day 1 or day 2. Multivariant analysis of 12 variables including the highest and lowest S, D, and M BP on day 1 and day 2 failed to show any significant differences. The variability of BP was evaluated by determining the coefficient of variation (CV) for all the available measurements of S and D BP for each of the first 2 days. There were no differences in the CV between the 3 groups on either day by analysis of variance. Thus, for LBW infants with respiratory distress we were unable to demonstrate a relationship between the course of the systemic BP over the first 2 days of life and the incidence or severity of IVH.
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Batton, D., Gardyasz, M., Boal, D. et al. 1335 SYSTEMIC BLOOD PRESSURE (BP), RESPIRATORY DISTRESS, AND INTRAVENTRICULAR HEMORRHAGE (IVH) IN LOW BIRTH WEIGHT (LBW) INFANTS. Pediatr Res 19, 333 (1985). https://doi.org/10.1203/00006450-198504000-01359
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DOI: https://doi.org/10.1203/00006450-198504000-01359