Abstract
Synovial sarcoma (SS) is a rare malignancy in adults and children. Between 1976 and 1981 5 patients with SS were seen on our pediatric oncology service. All were male, 2 were black and ages ranged from 5½ to 22 yrs., median 14. Sites of origin were the mid-back, ankle, popliteal fossa, thigh and upper arm. Histologically 3 were bimorphic and 2 monomorphic. No patient had evidence of metastasis (METS) at diagnosis. Initial surgery included incomplete resection (IR) in 2 and complete resection (CR) in 3. In the 2 patients with IR, 1 had 2nd surgery with CR and 1 refused amputation. All patients received adjuvant "sarcoma type" VACA chemotherapy (CT) and the 2 with initial IR had local radiation. Outcome is shown below:
We conclude that SS in the young is not well controlled with local XRT and standard VACA therapy. Complete tumor excision should be the primary goal and other chemotherapy regimens investigated.
Article PDF
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
McWilliams, N., Dunn, N., Maurer, H. et al. SYNOVIAL SARCOMA IN CHILDREN AND YOUNG ADULTS. Pediatr Res 18 (Suppl 4), 245 (1984). https://doi.org/10.1203/00006450-198404001-00911
Issue Date:
DOI: https://doi.org/10.1203/00006450-198404001-00911