Abstract
Percutaneous renal biopsies were performed in 61 non-uremic children between 1963 and 1982 for unexplained hematuria. In 26 biopsies, only attenuation of the lamina densa of the glomerular capillary wall (BM) was found by electron microscopy (EM), a finding consistent with BM nephropathy. Of these 26 children, 16 had microscopic hematuria (MH) found on routine urinalysis and 10 had gross hematuria (GH) (7 associated with fever or physical exercise, 3 with no associated event). In 18 biopsies, findings diagnostic of IgA nephropathy were present. Of these 18 children, 12 had GH (5 with fever or phsyical activity and 7 without associated event). In the last group of 17 biopsies, no specific diagnostic findings were present, the biopsies being either normal (12 cases) or showing only mino non-specific glomerular alterations (5 cases). Of these 17 children, 10 had MH and 7 GH, all without associated event.
Conclusion: The renal biopsy is diagnostic in 72.1% of children with unexplained hematuria.
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Piel, C., Biava, C. & Goodman, J. UNEXPLAINED HEMATURIA: HISTOLOGIC DIAGNOSIS IN 61 CHILDREN. Pediatr Res 18 (Suppl 4), 367 (1984). https://doi.org/10.1203/00006450-198404001-01644
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DOI: https://doi.org/10.1203/00006450-198404001-01644
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