Abstract
The results of local experience in serological diagnosis of toxoplasmosis with DAT with and without 2 Mercaptoethanol (2-ME) in a pediatric population are described. Indirect fluorescent antibody tests (IFA) and complement fixation tests were performed in the same samples. 30 serum samples taken from 14 patients and some of their mothers were divided into three groups: a) congenital toxoplasmosis, (3 infants below the age of 6 months); b) corioretinitis probably due to toxoplasmosis, assumed on the basis of type of lesion and serology (5 patients aged 10 to 19 months); and c) acute toxoplasmosis, (6 children aged 3 to 10 years).
Titres obtained with DAT ranged from 1/256 to 1/64,000, and were concordant to clinical data. The fall of titres obtained with 2ME had diagnostic value in 2 patients from group C. IFA showed a similar pattern of results, but it was negative in 1 acute patient with a positive DAT.
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Freilij, H., Gómez, J. & Grinstein, S. 23 DIAGNOSTIC VALUE OF DIRECT AGLUTINATION TEST (DAT) IN TOXOPLASMOSIS IN CHILDHOOD. Pediatr Res 15, 187 (1981). https://doi.org/10.1203/00006450-198102000-00080
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DOI: https://doi.org/10.1203/00006450-198102000-00080