Abstract
Recently, a method for the purification of blood by the use of high flux membrane or charcoal has become an accepted measure for treatment of chronic uremia in children. Since 1979, six children aged 1 to 16 years and weighing 8 to 50 kg were treated by hemodiafiltration (HDF) or hemodialysis with charcoal for 1 to 6 months in preparation for renal transplants. Three patients were treated by HDF twice weekly for 4 hour periods, using either 6 layers of PAN membrane or PMMA membrane. Two patients were treated by conventional dialysis with 100 gm charcoal in series twice weekly for 4 hour periods. Results were satisfactory as compared to conventional dialysis. An average reduction of BUN, Creatinine and Phosphate during 4 hours HDF was 66.7(%), 59.3(%) and 48.3(%) respectively. In combination series, an average reduction of BUN,Creatinine and Phosphate was 68.3(%), 64.0(%) and 46.2(%) respectively during 4 hours treatment period. Symptoms and signs were very few in each session. In conclusion, extended blood purification by the use of high flux membrane or charcoal are feasible even for small children or infants.
Article PDF
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Sakai, T., Iitaka, K., Kumano, K. et al. A NEW METHOD FOR THE PURIFICATION OF BLOOD IN CHILDREN WITH CHRONIC RENAL FAILURE. Pediatr Res 14, 994 (1980). https://doi.org/10.1203/00006450-198008000-00124
Issue Date:
DOI: https://doi.org/10.1203/00006450-198008000-00124