Abstract
A prospective study of the administration of Vitamin E Injectable (Roche) was performed to evaluate use in possible prevention of retinopathy of prematurity utilizing the techniques of fundus photography and fluorescein angiography in conjunction with indirect ophthalmoscopy to increase detection of early vascular lesions of retinopathy of prematurity. Study population consists of infants with birthweight <1500 gms, alternate infants given 50 mgm/kg/d × 3 beginning at <6 hours after birth with consent from the parents. Vitamin E levels and results follow:
Although the sample size is small, fluorescein angiography suggests a possible beneficial effect of Vitamin E injectable administration at birth in decreasing the incidence of retinopathy of prematurity and warrants further study.
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Curran, J., Cantolino, S. & Barness, L. 241 VITAMIN E (INJECTABLE) ADMINISTRATION IN THE PREVENTION OF RETINOPATHY OF PREMATURITY: EVALUATION WITH FLUORESCEIN ANGIOGRAPHY AND FUNDUS. Pediatr Res 12 (Suppl 4), 404 (1978). https://doi.org/10.1203/00006450-197804001-00246
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DOI: https://doi.org/10.1203/00006450-197804001-00246