Abstract
Einstein Medical College, Bronx-Lebanon Hospital Ctr. Dept. Ped. & SUNY-Downstate Medical Ctr., Brooklyn. We have analyzed the relationship between RDS and maternal toxemia in 2107 premature infants weighing between 1000 and 2199 g born from Jan.1968 to Dec.1975 at Downstate Medical Center. Two-hundred and forty-six mothers developed toxemia. The incidence of RDS (15%) in the toxemia group was significantly (p<0.001) lower than that (30%) in the non-toxemia group. In infants whose gestational age was 34 wk or less, the incidence was 21% in the toxemia group and 35% in the non-toxemia group (p<0.001). In infants whose gestational age was 35 wk or more, the incidence (6%) in the toxemia group was significantly (p<0.05) lower than that (15%) in the non-toxemia group. Toxemia was classified into 6 groups; mild pre-eclampsia (1),severe pre-eclampsia (2),antepartum eclampsia (3), intrapartum eclampsia (4),hypertensive before pregnancy with toxemia (5),hypertensive before pregnancy without toxemia (6). The incidence of RDS was 21% in group 1,13% in 2,9% in 3, 0% in 4,10% in 5 and 15% in 6. It appears that the incidence of RDS was inversely related to the severity of maternal toxemia (group 1-4). The incidence of RDS was significantly (p<0.005) lower in infants of mothers who had hypertension before pregnancy with or without toxemia. Our study demonstrated the low incidence of RDS in premature infants of toxemic mothers and inverse relationship between the development of RDS and the severity of maternal toxemia.
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Yoon, J., Kohl, S. & Cook, C. 1039 THE RELATIONSHIP BETWEEN THE INCIDENCE OF RESPIRATORY DISTRESS SYNDROME (RDS) AND MATERNAL TOXEMIA. Pediatr Res 12 (Suppl 4), 537 (1978). https://doi.org/10.1203/00006450-197804001-01045
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DOI: https://doi.org/10.1203/00006450-197804001-01045