Abstract
The effects of the time of application of CPAP on the mortality and morbidity of HMD were examined in 36 infants in 3 weight groups (<1200, 1201-1800 and ≥1801 gms). Infants were randomly assigned by weight group to early (E) or late (L) CPAP by nasal prongs when PaO2≤50 mgHg while breathing in FIO2=0.4 or 0.7, respectively. Results are shown below:
There were no differences in mortality, need for artificial ventilation, time spent in an FIO2>0.3 or >0.7 or in the incidence of air leak or chronic lung disease. Eleven of nineteen infants assigned to late CPAP never required an FIO2≥0.7 and did not receive CPAP. The present study suggests that the early application of CPAP offers no measurable advantage over the late application of CPAP in the treatment of mild HMD.
Article PDF
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Rowe, J., Guthrie, R., Hinkes, P. et al. 1017 TIME OF INITIATION OF CPAP IN HMD. Pediatr Res 12 (Suppl 4), 533 (1978). https://doi.org/10.1203/00006450-197804001-01023
Issue Date:
DOI: https://doi.org/10.1203/00006450-197804001-01023
This article is cited by
-
A review on noninvasive ventilation: The Cochrane Systematic Reviews 2006
Journal of Perinatology (2007)