Abstract
The ZSR has certain technical advantages over the erythrocyte sedimentation rate (ESP), and is not influenced by the presence of anemia. A study was undertaken to establish normal values for the ZSR In infants and children, and to compare the diagnostic utility of the ZSR as opposed to the ESR in children believed to hove active inflammatory processes. The normal values for the ZSP in infants and younger children (mean ±2SD) were significantly lower than in the older age group:
The ESR showed a similar, although not statistically significant trend. TVere were 6 children considered normal who, however, had increased ESRs but normal ZSRs. 4/6 were anemic, and may therefore have had falsely elevated ESR values. Among the 70 tests obtained on children believed to have clinically active inflammatory processes, 2/70 (3%) had normal ZSRs and ESRs. 6/70 (9%) had increased ERRs with concomitantly normal ZSRs, whereas 6/70 (9%) had normal ESRs with elevated ZSRs. These findings suggest that the ZSR is comparable to the ESR as an index of disease, and is recommended as a technically superior substitute for the ESR in infants and children.
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Campbell, J., Stuart, M. & Nelson, D. THE ZETA SEDIMENTATION RATE (ZSR) IN CHILDREN. Pediatr Res 11, 468 (1977). https://doi.org/10.1203/00006450-197704000-00592
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DOI: https://doi.org/10.1203/00006450-197704000-00592