Abstract
In 10 healthy male prematures (birth weight 1750-2270 g, gestional age 33-34 weeks) acid-base balance studies were performed, Meb, a formula adapted to human milk, was given. Urine was collected over the first 10 days of life and examined for net acid excretion (NAE) equivalent to titratable acidity (TA) + NH4 - HCO3, as well as for organic acids (OA), sulfate (SO4) and other electrolytes. Selected results are recorded below for 3 representative days of the following periods: period A (days 1+2), period B (days 3+4) period C (days 5-10).
These results suggest, that the increasing NAE during the first 10 days of life is due to the change from the catabolic to the anabolic state and to the increasing electrolyte excretion concerning predominantly the anions. The high NAE observed on feeding the formula reflects an inadequate electrolyte composition in contrast to human milk.
Article PDF
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Manz, F., Wille, L. & Schärer, K. 133: Acid-base balance during the first 10 days of life in prematures. Pediatr Res 10, 892 (1976). https://doi.org/10.1203/00006450-197610000-00124
Issue Date:
DOI: https://doi.org/10.1203/00006450-197610000-00124