Abstract
Biodegradable hydrogels based on synthetic PHEA and IPN type composite hydrogel with chitosan, a natural carbohydrate polymer, were prepared by crosslinking using glutaraldehyde in aqueous mixture. Relatively strong hydrogels were formed in a shaped mold. Preparation of crosslinked gels and their swelling behavior depending on the composition, medium, and pH of solution are investigated. The porous morphology of scaffolds, obtained by freeze-drying method, was observed by scanning electron microscopy. Also preliminary results on hydrolytic degradation and cytotoxicity test of the hydrogel are included.
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Kim, J., Sim, S., Lee, D. et al. Preparation and Properties of PHEA/Chitosan Composite Hydrogel. Polym J 36, 943–948 (2004). https://doi.org/10.1295/polymj.36.943
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DOI: https://doi.org/10.1295/polymj.36.943
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