Long noncoding RNAs (lncRNAs) have divergent roles in the nuclei of higher eukaryotes, including chromatin modification and regulation of nuclear bodies. A new study adds a new lncRNA function to the current list: serving as a platform for trans-chromosomal associations. At least three gene loci located on different chromosomes are brought together around the transcription site of a lncRNA termed functional intergenic repeating RNA element (Firre).
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Nakagawa, S., Hirano, T. Gathering around Firre. Nat Struct Mol Biol 21, 207–208 (2014). https://doi.org/10.1038/nsmb.2782
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DOI: https://doi.org/10.1038/nsmb.2782