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The ABCs of the ribosome

An ABC protein that binds the ribosomal exit site suggests a new mechanism for direct regulation of translation in response to changing ATP levels in the cell.

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Figure 1: ABC proteins bind to different sites on the ribosome.

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Acknowledgements

We thank J. Frank, B. Chen and M. Thomas for providing the figure. Work on translation in the authors' labs is supported by grants from the US National Institutes of Health (GM 072528 to K.F. and GM065183 to M.I.).

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Correspondence to Kurt Fredrick or Michael Ibba.

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Fredrick, K., Ibba, M. The ABCs of the ribosome. Nat Struct Mol Biol 21, 115–116 (2014). https://doi.org/10.1038/nsmb.2765

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