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Antiviral RNA interference in animals: piecing together the evidence

Nature Structural & Molecular Biology volume 20, pages 1239–1241 (2013)Cite this article

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RNA interference (RNAi) is a powerful mechanism to fight viral infections in plants and invertebrates. Two recent reports provide new, compelling evidence for a functional role for antiviral RNAi in mammals.

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Figure 1: Schematic viral cycle of positive-strand RNA viruses.
Figure 2: Overview of antiviral pathways in mammals, plants and invertebrates, with a focus on RNA viruses.

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Authors and Affiliations

  1. Mélanie Tanguy and Eric A. Miska are at the Wellcome Trust and Cancer Research UK Gurdon Institute and Department of Genetics, University of Cambridge, Cambridge, UK.,

    Mélanie Tanguy & Eric A Miska

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  1. Mélanie Tanguy
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  2. Eric A Miska
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Correspondence to Eric A Miska.

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Tanguy, M., Miska, E. Antiviral RNA interference in animals: piecing together the evidence. Nat Struct Mol Biol 20, 1239–1241 (2013). https://doi.org/10.1038/nsmb.2708

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