Members of the family of fungal Zn2Cys6 DNA-binding proteins discriminate between their DNA targets using neither their DNA-binding module, nor their dimerization domain, but primarily through the relatively flexible linker between them.
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References
Walters, K.J., Dayie, K.T., Reece, R.J., Ptashne, M. & Wagner, G. Nature Struct Biol. 4, 744–750 (1997).
Swaminathan, K., Flynn, P., Reece, R.J. & Marmorstein, R. Nature Struct. Biol. 4, 751–759 (1997).
Rhodes, D., Schwabe, J.W.R., Chapman, L. & Fairall, L. Phil. Trans. R. Soc. Lond. B 351, 501–509 (1996).
Schjerling, P. & Holmberg, S. Nucleic Acids Res. 24, 4599–4607 (1996).
Baleja, J.D., Marmorstein, R., Harrison, S.C. & Wagner, G. Nature 356, 450–453 (1992).
Kraulis, P.J., Raine, A.R.C., Gadhavi, P.L. & Laue, E.D. Nature 356, 448–450 (1992).
Gardner, K.H., Anderson, S.F. & Coleman, J.E. Nature Struct. Biol. 2, 898–905 (1995).
Timmerman, J., et al. J. Mol. Biol. 259, 792–804 (1996).
Marmorstein, R., Carey, M., Ptashne, M. & Harrison, S.C. Nature 356, 408–414 (1992).
Marmorstein, R. & Harrison, S.C. Genes Dev. 8, 2504–2512 (1994).
Reece, R.J. & Ptashne, M. Science 261, 909–911 (1993).
Zhang, L. & Guarente, L. Genes Dev. 8, 2110–2119 (1994).
Hellauer, K., Rochon, M.H. & Turcotte, B. Mol. Cell. Biol. 16, 6096–6102 (1996).
Schwabe, J.W.R., Chapman, L., Finch, J.T., Rhodes, D. & Neuhaus, D. Structure 1, 187–204 (1993).
Liang, S.D., Marmorstein, R., Harrison, S.C. & Ptashne, M. Mol. Cell Biol. 16, 3773–3780 (1996).
Siddiqui, A.H. & Brandriss, M.C. Mol. Cell. Biol. 9, 4706–4712 (1989).
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Schwabe, J., Rhodes, D. Linkers made to measure. Nat Struct Mol Biol 4, 680–683 (1997). https://doi.org/10.1038/nsb0997-680
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DOI: https://doi.org/10.1038/nsb0997-680