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And the Best Picture is — the HIV gp120 envelope, please!

Abstract

X-ray crystallographic structure of the gp 120 core coupled with mutagenesis analyses reveal details of receptor interactions and multiple layers of immune evasion.

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Figure 1: Ternary complex between the gp120 core (red), CD4 D1D2 (yellow) and Fab 17b light chain (blue) and heavy chain (purple).
Figure 2: Core gp120 showing the inner domain, outer domain, and bridging sheet.

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Correspondence to Edward A. Berger.

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Berger, E. And the Best Picture is — the HIV gp120 envelope, please!. Nat Struct Mol Biol 5, 671–674 (1998). https://doi.org/10.1038/1362

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