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Crystal structure of the actin-binding protein actophorin from Acanthamoeba

Nature Structural Biology volume 4, pages 369–373 (1997)Cite this article

Actophorin is a member of the actin-depolymerizing factor/cofilin family. It severs act in filaments and sequesters actin monomers. The crystal structure of actophorin will help to elucidate actin–ADF/cofilin interactions.

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Author information

Author notes

  1. Eugene C. Petrella

    Present address: 3-Dimensional Pharmaceutical, 665 Stockton Drive, Exton, PA, 19341

  2. Thomas D. Pollard

    Present address: Salk Institute for Biological Studies, 10010 N. Torrey Pines Road, La Jolla, CA, 92037

Authors and Affiliations

  1. Department of Biophysics and Biophysical Chemistry, Hopkins School of Medicine, 725 N. Wolfe Street, Baltimore, MD, 21205

    Shonda A. Leonard, Apostolos G. Gittis & Eaton E. Lattman

  2. Department of Cell Biology and Anatomy, Johns Hopkins School of Medicine, 725 N. Wolfe Street, Baltimore, MD, 21205

    Eugene C. Petrella & Thomas D. Pollard

Authors
  1. Shonda A. Leonard
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  2. Apostolos G. Gittis
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  3. Eugene C. Petrella
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  4. Thomas D. Pollard
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  5. Eaton E. Lattman
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Leonard, S., Gittis, A., Petrella, E. et al. Crystal structure of the actin-binding protein actophorin from Acanthamoeba. Nat Struct Mol Biol 4, 369–373 (1997). https://doi.org/10.1038/nsb0597-369

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