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A double-take on MAPs

Nature Structural & Molecular Biology volume 10, pages 314–316 (2003)Cite this article

Structural characterization of the DCX domains from doublecortin reveals novel mechanisms for microtubule binding in a protein essential for brain development.

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References

  1. Olson, E.C. & Walsh, C.A. Curr. Opin. Genet. Dev. 12, 320–327 (2002).

    Article  CAS  PubMed  Google Scholar 

  2. Reiner, O. et al. Nature 364, 717–721 (1993).

    Article  CAS  PubMed  Google Scholar 

  3. des Portes, V. et al. Cell 92, 51–61 (1998).

    Article  CAS  PubMed  Google Scholar 

  4. Gleeson, J.G. et al. Cell 92, 63–72 (1998).

    Article  CAS  PubMed  Google Scholar 

  5. Schultz, J., Milpetz, F., Bork, P. & Ponting, C.P. Proc. Natl. Acad. Sci. USA 95, 5857–5864 (1998).

    Article  CAS  Google Scholar 

  6. Kim, M.H. et al. Nat. Struct. Biol. 10, 324–333 (2003).

    Article  CAS  PubMed  Google Scholar 

  7. Gleeson, J.G. Curr. Opin. Neurol. 13, 121–125 (2000).

    Article  CAS  PubMed  Google Scholar 

  8. Francis, F. et al. Neuron 23, 247–256 (1999).

    Article  CAS  PubMed  Google Scholar 

  9. Gleeson, J.G., Lin, P.T., Flanagan, L.A. & Walsh, C.A. Neuron 23, 257–271 (1999).

    Article  CAS  PubMed  Google Scholar 

  10. Horesh, D. et al. Hum. Mol. Gen. 8, 1599–1610 (1999).

    Article  CAS  PubMed  Google Scholar 

  11. Sapir, T. et al. Hum. Mol. Gen. 9, 703–712 (2000).

    Article  CAS  PubMed  Google Scholar 

  12. Taylor, K.R., Holzer, A.K., Bazan, J.F., Walsh, C.A. & Gleeson, J.G. J. Biol. Chem. 275, 34442–34450 (2000).

    Article  CAS  PubMed  Google Scholar 

  13. Gönczy, P. et al. Dev. Cell 1, 363–375 (2001).

    Article  PubMed  Google Scholar 

  14. Li, S. et al. J. Biol. Chem. 277, 48596–46601 (2002).

    Article  CAS  PubMed  Google Scholar 

  15. Geyer, M., Herrmann, C., Wohlegemuth, S., Wittinghofer, A. & Kalbitzer, R. Nat. Struct. Biol. 4, 694–699 (1997).

    Article  CAS  PubMed  Google Scholar 

  16. Iakoucheva, L.M., Brown, C.J., Lawson, J.D., Obradovic, Z. & Dunker, A.K. J. Mol. Biol. 323, 573–584 (2002).

    Article  CAS  PubMed  Google Scholar 

  17. Dunker, A.K., Brown, C.J., Lawson, J.D., Iakoucheva, L.M. & Obradovic, Z. Biochemistry 41, 6573–6582 (2002).

    Article  CAS  Google Scholar 

  18. Wright, P.E. & Dyson, H.J. J. Mol. Biol. 293, 321–331 (1999).

    Article  CAS  Google Scholar 

  19. Cassimeris, L. & Spittle, C. Int. Rev. Cytol. 210, 163–226 (2001).

    Article  CAS  Google Scholar 

  20. Vale, R.D. & Milligan, R.A. Science 288, 88–95 (2000).

    Article  CAS  Google Scholar 

  21. Al-Bassam, J., Ozer, R.S., Safer, D., Halpain, S. & Milligan, R.A. J. Cell Biol. 157, 1187–1196 (2002).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  22. Hoogenraad, C.C., Akhmanova, A., Grosveod, F., De Zeeuw, C.I., Galjart, N. J. Cell Sci. 113, 2285–2297 (2000).

    CAS  PubMed  Google Scholar 

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Authors and Affiliations

  1. Department of Cell Biology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, 92037, California, USA

    Carolyn A. Moores

  2. Laboratoire de Génétique et Physiopathologie des Retards Mentaux, GDPM, Institut Cochin, 24, rue du Faubourg Saint Jacques, Paris, 75014, France

    Fiona Francis

  3. Motilité Structurale, Institut Curie CNRS, UMR 144, 26 rue d'Ulm, Paris, 75248, Cedex 05, France

    Mylène Perderiset & Anne Houdusse

Authors
  1. Carolyn A. Moores
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  2. Fiona Francis
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  3. Mylène Perderiset
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  4. Anne Houdusse
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Correspondence to Anne Houdusse.

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Moores, C., Francis, F., Perderiset, M. et al. A double-take on MAPs. Nat Struct Mol Biol 10, 314–316 (2003). https://doi.org/10.1038/nsb0503-314

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