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Incontinence

The dilemma with comparing efficacy of OAB treatments

The comparative efficacy of drugs for the management of overactive bladder syndrome (OAB) remains undefined. A new indirect treatment comparison demonstrates similar efficacy of mirabegron versus several antimuscarinic drugs and onabotulinum toxin A in a number of outcome measures. Head-to-head trials of these agents are still required to optimize the management of patients with OAB.

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Correspondence to Arun Sahai.

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Competing interests

A.S. has received an unrestricted educational grant and has been an adviser for Allergan. A.S. has received payment for lectures on behalf of Allergan, Astellas and Pfizer. S.M. declares no competing interests.

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Sahai, A., Malde, S. The dilemma with comparing efficacy of OAB treatments. Nat Rev Urol 14, 393–394 (2017). https://doi.org/10.1038/nrurol.2017.67

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