Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • News & Views
  • Published:

Kidney cancer

Undertreatment of small renal masses by overuse of biopsy

Recent evidence from series of small renal mass biopsy samples and methodologically robust meta-analyses provides improved guidance on cost–benefit trade-offs for diagnosis and management of this disease. Renal mass biopsy sampling should be reserved for situations in which it will affect management decisions – which it will not do for all patients.

This is a preview of subscription content, access via your institution

Relevant articles

Open Access articles citing this article.

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

References

  1. Patel, H. D. & Pierorazio, P. M. Small renal mass — to biopsy or not? The role of biopsy in evaluation. Eur. Urol. Focus. 2, 154–155 (2016).

    Article  Google Scholar 

  2. Kutikov, A. et al. Renal mass biopsy: always, sometimes, or never? Eur. Urol. 70, 403–406 (2016).

    Article  Google Scholar 

  3. Halverson, S. J. et al. Accuracy of determining small renal mass management with risk stratified biopsies: confirmation by final pathology. J. Urol. 189, 441–446 (2013).

    Article  Google Scholar 

  4. Ambani, S. N. et al. Predictors of delayed intervention for patients on active surveillance for small renal masses: does renal mass biopsy influence our decision? Urology http://dx.doi.org/10.1016/j.urology.2016.04.067 (2016).

  5. Richard, P. O. et al. Safety, reliability and accuracy of small renal tumor biopsies: results of a multi-institution registry. BJU Int. http://dx.doi.org/10.1111/bju.13630 (2016).

  6. Patel, H. D. et al. Diagnostic accuracy and risks of biopsy in the diagnosis of a renal mass suspicious for localized renal cell carcinoma: systematic review of the literature. J. Urol. 195, 1340–1347 (2016).

    Article  PubMed Central  Google Scholar 

  7. Marconi, L. et al. Systematic review and meta-analysis of diagnostic accuracy of percutaneous renal tumour biopsy. Eur. Urol. 69, 660–673 (2016).

    Article  Google Scholar 

  8. Patel, H. D. et al. A prospective, comparative study of quality of life among patients with small renal masses choosing active surveillance and primary intervention. J. Urol. 196, 1356–1362 (2016).

    Article  Google Scholar 

  9. Pierorazio, P. M. et al. Distinguishing malignant and benign renal masses with composite models and nomograms: a systematic review and meta-analysis of clinically localized renal masses suspicious for malignancy. Cancer http://dx.doi.org/10.1002/cncr.30268 (2016).

  10. Patel, H. D. et al. A systematic review of research gaps in the evaluation and management of localized renal masses. Urology http://dx.doi.org/10.1016/j.urology.2016.08.013 (2016).

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Phillip M. Pierorazio.

Ethics declarations

Competing interests

The authors declare no competing financial interests.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Patel, H., Pierorazio, P. Undertreatment of small renal masses by overuse of biopsy. Nat Rev Urol 13, 701–703 (2016). https://doi.org/10.1038/nrurol.2016.213

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/nrurol.2016.213

This article is cited by

Search

Quick links

Nature Briefing: Cancer

Sign up for the Nature Briefing: Cancer newsletter — what matters in cancer research, free to your inbox weekly.

Get what matters in cancer research, free to your inbox weekly. Sign up for Nature Briefing: Cancer