Children with myelomeningocele or lipomyelomeningocele requiring spinal detethering were randomized to receive detethering with or without the Xiao procedure. Double-blind evaluations over 3 years of follow-up monitoring showed no difference in voluntary voiding or continence, and evaluators were unable to predict to which group each patient had been randomized.
References
Tuite, G. F. et al. Urologic outcome of the Xiao procedure in children with myelomeningocele and lipomyelomeningocele undergoing spinal cord detethering: results of a randomized, prospective, double blind study. J. Urol. http://dx.doi.org/10.1016/j.juro.2016.05.111 (2016)
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Fenner, A. Randomized study of the Xiao procedure. Nat Rev Urol 13, 437 (2016). https://doi.org/10.1038/nrurol.2016.123
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DOI: https://doi.org/10.1038/nrurol.2016.123