Cases of systemic lupus erythematosus with onset during childhood seem to be more severe than adult-onset disease, possibly because of genetic influences. But is more-detailed information about the molecular heterogeneity of the disease needed in order to tailor treatments and improve prognosis?
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Cimaz, R. Phenotype and prognosis of juvenile systemic lupus erythematosus. Nat Rev Rheumatol 12, 382–383 (2016). https://doi.org/10.1038/nrrheum.2016.101
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DOI: https://doi.org/10.1038/nrrheum.2016.101
