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Osteoarthritis

OA guidelines: improving care or merely codifying practice?

Updated guidelines from the Osteoarthritis Research Society International and the UK's National Institute for Health and Care Excellence provide a clear summary of the evidence supporting current therapeutic strategies in osteoarthritis (OA), but in reality they serve to highlight the inability of modern medicine to fully relieve OA pain and dysfunction.

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References

  1. Hochberg, M. C. et al. American College of Rheumatology 2012 recommendations for the use of nonpharmacologic and pharmacologic therapies in osteoarthritis of the hand, hip, and knee. Arthritis Care Res. 64, 465–474 (2012).

    Article  CAS  Google Scholar 

  2. American Academy of Orthopaedic Surgeons. Treatment of osteoarthritis of the knee: evidence-based guideline, 2nd ed. [online], (2014).

  3. McAlindon, T. E. et al. OARSI guidelines for the non-surgical management of knee osteoarthritis. Osteoarthritis Cartilage 22, 363–388 (2014).

    Article  CAS  PubMed  Google Scholar 

  4. National Institute for Health and Care Excellence (UK). Osteoarthritis: care and management in adults (CG177) [online], (2014).

  5. Zhang, W., Robertson, J., Jones, A. C., Dieppe, P. A. & Doherty, M. The placebo effect and its determinants in osteoarthritis: meta-analysis of randomised controlled trials. Ann. Rheum. Dis. 67, 1716–1723 (2008).

    Article  CAS  PubMed  Google Scholar 

  6. Sawitzke, A. D. et al. Clinical efficacy and safety of glucosamine, chondroitin sulphate, their combination, celecoxib or placebo taken to treat osteoarthritis of the knee: 2-year results from GAIT. Ann. Rheum. Dis. 69, 1459–1464 (2010).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  7. Block, J. A. & Shakoor, N. Lower limb osteoarthritis: biomechanical alterations and implications for therapy. Curr. Opin. Rheumatol. 22, 544–550 (2010).

    Article  PubMed  Google Scholar 

  8. Lawrence, R. C. et al. Estimates of the prevalence of arthritis and other rheumatic conditions in the United States. Part II. Arthritis Rheum. 58, 26–35, (2008).

    Article  PubMed  PubMed Central  Google Scholar 

  9. Weinstein, A. M. et al. Estimating the burden of total knee replacement in the United States. J. Bone Joint Surg. Am. 95, 385–392 (2013).

    Article  PubMed  PubMed Central  Google Scholar 

  10. Bedson, J. & Croft, P. R. The discordance between clinical and radiographic knee osteoarthritis: a systematic search and summary of the literature. BMC Musculoskelet. Disord. 9, 116 (2008).

    Article  PubMed  PubMed Central  Google Scholar 

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Correspondence to Joel A. Block.

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Competing interests

J.A.B. is Associate Editor of Osteoarthritis & Cartilage, which is owned by OARSI, and Chair of the ACR Committee on Education.

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Block, J. OA guidelines: improving care or merely codifying practice?. Nat Rev Rheumatol 10, 324–326 (2014). https://doi.org/10.1038/nrrheum.2014.61

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