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Spondyloarthritis

From undifferentiated SpA to ankylosing spondylitis

Clinical findings and responses to biologic agents are increasing the evidence that undifferentiated spondyloarthritis (SpA) may represent the earliest stage of ankylosing spondylitis and psoriatic arthritis. New results also lend support to the hypothesis that the SpA spectrum represents one clinical condition, but hurdles in improving classification and diagnosis remain.

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Figure 1: Schematic representation of the relationship between the diseases and conditions that constitute adult-onset SpA.

References

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Correspondence to Rubén Burgos-Vargas.

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Burgos-Vargas, R. From undifferentiated SpA to ankylosing spondylitis. Nat Rev Rheumatol 9, 639–641 (2013). https://doi.org/10.1038/nrrheum.2013.146

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