That primary osteoarthritis (OA) is an age-related disorder is undoubted, but how aging contributes to OA is poorly understood. New insights from 2011 offer potential explanations, novel models for study, and the suggestion that a deeper understanding of what 'aging' actually is might pave the way to everlasting joints.
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Acknowledgements
We acknowledge the support of the DFG for our work (grant numbers Ai 20/7-1,2 and Ri 707/7-1).
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Aigner, T., Richter, W. Age-related OA—a concept emerging from infancy?. Nat Rev Rheumatol 8, 70–72 (2012). https://doi.org/10.1038/nrrheum.2011.206
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DOI: https://doi.org/10.1038/nrrheum.2011.206
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