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Rheumatoid arthritis

Repair of erosion in RA—shifting the balance to formation

Nature Reviews Rheumatology volume 7, pages 626–628 (2011)Cite this article

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Repair of bone erosions in rheumatoid arthritis has been considered a difficult goal to achieve. However—with better therapies at hand to control synovial inflammation—sensitive μCT imaging techniques now available confirm that repair of bone erosion is possible, and begins at the base of erosive lesions.

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Figure 1: TNF—a multipotent cytokine in RA.

References

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Acknowledgements

The work of E. M. Gravallese is supported by NIH grant AR055952. The work of N. C. Walsh is supported by an Australian National Health and Medical Research Council project grant.

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Authors and Affiliations

  1. Rheumatology Division, Department of Medicine, University of Massachusetts Medical School, 364 Plantation Street, Suite 223, Worcester, 01605, MA, USA

    Ellen M. Gravallese

  2. St Vincent's Institute of Medical Research, 9 Princes Street, Fitzroy, 3065, VIC, Australia

    Nicole C. Walsh

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  1. Ellen M. Gravallese
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  2. Nicole C. Walsh
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Correspondence to Ellen M. Gravallese.

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Gravallese, E., Walsh, N. Repair of erosion in RA—shifting the balance to formation. Nat Rev Rheumatol 7, 626–628 (2011). https://doi.org/10.1038/nrrheum.2011.133

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