Biologic therapies that target interleukin (IL)-1 are known to dramatically improve symptoms of a group of rare, heritable chronic inflammatory diseases. The results of a phase III trial confirm the place of canakinumab in the treatment arsenal for these disorders.
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S. Savic and M. F. McDermott have acted as consultants for Novartis Pharma.
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Savic, S., McDermott, M. Canakinumab for the cryopyrin-associated periodic syndromes. Nat Rev Rheumatol 5, 529–530 (2009). https://doi.org/10.1038/nrrheum.2009.195
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DOI: https://doi.org/10.1038/nrrheum.2009.195
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