In adults, migraine with aura is associated with an increased risk of ischaemic stroke, but the relationship between migraine and paediatric stroke is not completely understood. Gelfand et al. analysed data from >1.4 million children and adolescents, including 88,164 migraineurs. Overall, there was no association between migraine and the risk of stroke in the paediatric population. However, a subgroup analysis revealed that migraine in adolescents (12–17 years) was linked to an increased risk of ischaemic stroke.