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Decade in review–stroke

Progress in acute ischaemic stroke treatment and prevention

Nature Reviews Neurology volume 11, pages 619–621 (2015)Cite this article

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Recent decades have seen a dramatic reduction in age-adjusted stroke-related mortality, presumably owing to better control of vascular risk factors, use of antithrombotic agents and improvements in acute stroke care. Here, we highlight a few developments in stroke prevention and acute care that have particularly influenced the care of patients.

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Figure 1: Association between time to recanalization and clinical outcomes in trials of mechanical endovascular recanalization.

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Acknowledgements

J.G.R. and R.L.S. have received research salary support from the NIH/NINDS (1R01NS29993, R01 NS40807 and and 1R01NS084288).

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  1. University of Miami, Miller School of Medicine, 1120 NW 14th Street, Miami, 33136, FL, USA

    Jose G. Romano & Ralph L. Sacco

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  1. Jose G. Romano
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Correspondence to Ralph L. Sacco.

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Competing interests

J.G.R. has received research support for MaRISS Study and honoraria from Genentech for a steering committee role, and honoraria and stock from Vycor NovaVision for a scientific advisory board role. R.L.S. has consulted for Boehringer Ingelheim as co-chair of the RESPECT-ESUS trial with dabigatran versus aspirin for secondary stroke prevention.

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Romano, J., Sacco, R. Progress in acute ischaemic stroke treatment and prevention. Nat Rev Neurol 11, 619–621 (2015). https://doi.org/10.1038/nrneurol.2015.199

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