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Stroke

Is thrombolysis safe in anticoagulated ischaemic stroke?

Intracerebral haemorrhage is the most serious complication of intravenous thrombolysis in ischaemic stroke, and whether thrombolysis can be performed in patients receiving anticoagulants is an unresolved issue. Data from a large European registry now confirms that thrombolysis in some patients receiving warfarin is as safe as in non-anticoagulated patients.

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Correspondence to Roland Veltkamp.

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Competing interests

R. Veltkamp has received consulting fees from Boehringer Ingelheim, Bayer, BMS/Pfizer and Roche; research support from Bayer and Boehringer Ingelheim; and speaker's honoraria from Bayer, Boehringer Ingelheim, BMS/Pfizer, Roche, Apoplex Medical Technologies and CSL Behring. T. Rizos declares no competing interests.

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Veltkamp, R., Rizos, T. Is thrombolysis safe in anticoagulated ischaemic stroke?. Nat Rev Neurol 9, 492–493 (2013). https://doi.org/10.1038/nrneurol.2013.159

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