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Neural repair and rehabilitation

The effect of therapeutic hypothermia on prognostication

Neurological markers are used to predict outcomes in patients resuscitated after cardiac arrest, and are crucial in informing treatment decisions in comatose patients. A multicenter study reports that therapeutic hypothermia in cardiac arrest alters the reliability of several recommended prognostic parameters, and the authors highlight challenges to optimization of prognostic paradigms.

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Acknowledgements

R. G. Geocadin is supported in part by NIH grant RO1-HL071568.

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Correspondence to Romergryko G. Geocadin.

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Geocadin, R., Kaplan, P. The effect of therapeutic hypothermia on prognostication. Nat Rev Neurol 8, 5–6 (2012). https://doi.org/10.1038/nrneurol.2011.201

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