A randomized, double-blind clinical trial that compared three widely used anticonvulsants for childhood absence epilepsy established that ethosuximide was the most appropriate first-line therapy for this condition. The study provides guidance for the treatment of this common childhood epilepsy where evidence-based recommendations have previously been lacking.
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Striano, P., Minetti, C. Old drugs do the trick in childhood absence epilepsy. Nat Rev Neurol 6, 420–421 (2010). https://doi.org/10.1038/nrneurol.2010.106
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DOI: https://doi.org/10.1038/nrneurol.2010.106