Drugs acting on the cholinergic system can improve or worsen cognitive abilities, and their effects are particularly pronounced in frail elderly individuals and patients with Alzheimer disease. Guidelines are urgently needed on the judicious use of cholinergic drugs.
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Desmarais, J., Gauthier, S. Clinical use of cholinergic drugs in Alzheimer disease. Nat Rev Neurol 6, 418–420 (2010). https://doi.org/10.1038/nrneurol.2010.105
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DOI: https://doi.org/10.1038/nrneurol.2010.105