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Multiple sclerosis

MRI—the perfect surrogate marker for multiple sclerosis?

Nature Reviews Neurology volume 5, pages 182–183 (2009)Cite this article

MRI provides a very sensitive reflection of the histopathological changes in multiple sclerosis. Many short-term studies fail to appreciate the relationship between MRI and clinical findings, although such shortcomings might be argued to reflect a weakness of clinical measures, rather than of MRI.

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Authors and Affiliations

  1. MS Center Amsterdam and Department of Radiology, Vrije Universiteit Medical Center, Amsterdam, The Netherlands

    Frederik Barkhof

  2. Neuroimaging Research Unit, Institute of Experimental Neurology, Scientific Institute and University Hospital San Raffaele, Milan, Italy

    Massimo Filippi

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  1. Frederik Barkhof
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  2. Massimo Filippi
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Correspondence to Frederik Barkhof.

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The authors declare no competing financial interests.

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Barkhof, F., Filippi, M. MRI—the perfect surrogate marker for multiple sclerosis?. Nat Rev Neurol 5, 182–183 (2009). https://doi.org/10.1038/nrneurol.2009.31

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