The incidence of cerebral microbleeds, which are acknowledged to be markers of hypertensive vasculopathy and cerebral amyloid angiopathy, increases with age. Cerebral microbleeds are particularly prevalent in patients with intracerebral hemorrhage, and a population-based, cross-sectional study indicates that they are also positively associated with antiplatelet drug use.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 12 print issues and online access
$209.00 per year
only $17.42 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
References
Greenberg, S. M. et al. Cerebral microbleeds: a guide to detection and interpretation. Lancet Neurol. 8, 165–174 (2009).
Vernooij, M. W. et al. Use of antithrombotic drugs and the presence of cerebral microbleeds: the Rotterdam Scan Study. Arch. Neurol. 66, 714–720 (2009).
Murray, F. E. et al. Comparison of effects of calcium carbasalate and aspirin on gastroduodenal mucosal damage in human volunteers. Gut 38, 11–14 (1996).
Vernooij, M. W. et al. Prevalence and risk factors of cerebral microbleeds: the Rotterdam Scan Study. Neurology 70, 1208–1214 (2008).
Koennecke, H. C. Cerebral microbleeds on MRI: prevalence, associations, and potential clinical implications. Neurology 66, 165–171 (2006).
Soo, Y. O. et al. Risk vs benefit of antithrombotic therapy in ischaemic stroke patients with cerebral microbleeds. J. Neurol. 255, 1679–1686 (2009).
Greenberg, S. M., Eng, J. A., Ning, M., Smith, E. E. & Rosand, J. Hemorrhage burden predicts recurrent intracerebral hemorrhage after lobar hemorrhage. Stroke 35, 1415–1420 (2004).
Lee, S. H., Ryu, W. I. & Roh, J. K. Cerebral microbleeds are a risk factor for warfarin-related intracerebral hemorrhage. Neurology 72, 171–176 (2009).
Fiehler, J. et al. Bleeding risk analysis in stroke imaging before thrombolysis (BRASIL): pooled analysis of T2*-weighted magnetic resonance imaging data from 570 patients. Stroke 38, 2738–2744 (2007).
Greenberg, S. M. et al. Microbleeds versus macrobleeds: evidence for distinct entities. Stroke 40, 2382–2386 (2009).
Author information
Authors and Affiliations
Corresponding author
Ethics declarations
Competing interests
The authors declare no competing financial interests.
Rights and permissions
About this article
Cite this article
McCarron, M., McVerry, F. Will cerebral microbleeds influence stroke prevention?. Nat Rev Neurol 5, 588–590 (2009). https://doi.org/10.1038/nrneurol.2009.165
Issue Date:
DOI: https://doi.org/10.1038/nrneurol.2009.165
