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Genetics of kidney disease in 2016

Ingenious tactics to unravel complex kidney disease genetics

The genetic background of many kidney diseases is complex and involves multiple genes, genetic variants and molecular pathways. Here, we look at how researchers tackled this challenging topic in 2016, focusing on studies that used ingenious data-integration tactics, which led to new insights into kidney disease aetiology and renal disease progression.

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Figure 1: Components that are essential for aetiological research strategies for the identification of contributors to complex kidney diseases.

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Correspondence to Nine V.A.M. Knoers.

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Renkema, K., Knoers, N. Ingenious tactics to unravel complex kidney disease genetics. Nat Rev Nephrol 13, 67–68 (2017). https://doi.org/10.1038/nrneph.2016.192

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