New research has assessed the effect of depression on the risk of developing chronic kidney disease (CKD) in patients with diabetes mellitus (DM). Novak et al. examined 933,211 American veterans with DM, of whom 340,806 had depression. They found that depression was associated with a 20% higher risk of developing CKD, increased all-cause mortality, and an increased incidence of cardiac events and stroke. The researchers suggest that intervention studies are needed to evaluate whether treatment of depression in patients with DM can reduce the risk of renal and cardiovascular complications.
References
Novak, M. et al. Increased risk of incident chronic kidney disease, cardiovascular disease, and mortality in diabetic patients with comorbid depression. Diabetes Care http://dx.doi.org/10.2337/dc16-0048 (2016)
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Aguilar, A. Depression is associated with renal complications. Nat Rev Nephrol 12, 444 (2016). https://doi.org/10.1038/nrneph.2016.105
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DOI: https://doi.org/10.1038/nrneph.2016.105
