Numerous studies in 2015 focused on therapeutic immune modulation and immunosuppression. Trials of budenoside in patients with IgA nephropathy who are unresponsive to supportive therapy, and of low-dose IL-2 to enforce regulatory T-cell-mediated immunosuppression in autoimmune disease all produced promising results.
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Acknowledgements
This work was supported by the Deutsche Forschungsgemeinschaft (grant numbers AN372/11-2, AN372/12-2, AN372/14-3, AN372/15-1, AN372/16-1, AN372/17-1).
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H-J.A. has received consultancy fees from GlaxoSmithKline, Roche, and Bayer.
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Anders, HJ. Updates on immunosuppression in kidney disease. Nat Rev Nephrol 12, 65–66 (2016). https://doi.org/10.1038/nrneph.2015.202
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DOI: https://doi.org/10.1038/nrneph.2015.202