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Chronic kidney disease

Should sodium intake be restricted in patients with CKD?

Nature Reviews Nephrology volume 10, pages 363–364 (2014)Cite this article

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A Correction to this article was published on 19 September 2016

This article has been updated

A reduction of salt intake to <5 g sodium chloride per day is generally advised for patients with chronic kidney disease. However, hard evidence to support this recommendation is lacking. New data from Fan et al. suggest that very strict sodium limits might be harmful in patients with renal disease.

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Figure 1: Potentially beneficial (green) and potentially deleterious (pink) effects of low dietary sodium intake on renal function.

Change history

  • 19 September 2016

    In the original published version of this article, a description of the association between urinary sodium excretion and kidney failure in patients with 24 h urinary sodium excretion <3 g per day was incorrect. The description has been corrected to read “Although no association was found between 24 h urinary sodium excretion and kidney failure in patients with urinary sodium excretion >3 g per day, when 24 h urinary sodium excretion was <3g per day, a 1g per day higher urine sodium was associated with a 72% increased risk of kidney failure in patients with baseline proteinuria <1g per day, and a 39% lower risk of kidney failure in patients with baseline proteinuria ≥1g per day.” The error has been corrected in the HTML and PDF versions of the article

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Acknowledgements

G.W.'s research is supported by Ambizione grants from the Swiss National Science Foundation (PZ00P3_121656 and PZ00P3_13262).

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Authors and Affiliations

  1. Service of Nephrology and Hypertension, Lausanne University Hospital, Rue du Bugnon 17, 1011, Lausanne, Switzerland

    Michel Burnier & Gregoire Wuerzner

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  1. Michel Burnier
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  2. Gregoire Wuerzner
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Correspondence to Michel Burnier.

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The authors declare no competing financial interests.

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Burnier, M., Wuerzner, G. Should sodium intake be restricted in patients with CKD?. Nat Rev Nephrol 10, 363–364 (2014). https://doi.org/10.1038/nrneph.2014.88

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